Navigating the terrifying corridors of the Care Center in Resident Evil 9 Requiem requires a keen eye for resources and puzzle solutions. Early in the East Wing, players will stumble upon a locked safe inside the Examination Room near a corpse. Opening this container provides crucial items that will significantly aid your survival efforts against the nightmarish threats lurking inside the facility.

Finding the Examination Room Safe

The locked safe itself is located on the first floor of the East Wing within the operating theater area. While it is easy to spot sitting on a shelf, the combination required to unlock it is locked behind natural story progression. You will need to explore deeper into the zone and deal with local hazards before the puzzle can be solved.

To obtain the actual combination file, players must head up to the second floor of the Care Center. Once you encounter the massive mutant enemy known as Chunk outside the Lead Researcher's Office, you can backtrack to safety. Returning to the locker area where this formidable boss first appeared will allow you to secure the note containing the necessary combination digits.

Standard and Casual Mode Combinations

For players enjoying the campaign on Standard or Casual difficulty settings, the puzzle solution remains consistent. The correct dial sequence required to crack the safe is 30 Right, 10 Left, and 50 Right. You must input these directions carefully in a fluid movement to ensure the mechanism registers correctly.

Successfully entering this code opens the door immediately and allows you to claim your hard-earned rewards. Inside the safe, you will discover three valuable Antique Coins waiting to be collected. These coins can eventually be traded in at the Parlor room to unlock permanent upgrades and highly useful inventory tools.

Cracking the Safe on Insanity Mode

For veteran survival horror enthusiasts tackling the brutal Insanity Mode, the game completely shifts item placements and puzzle answers. The developer altered the combinations on this higher difficulty level to test the mettle of experienced players. The Standard combination will not work, forcing you to adapt to the new layout constraints.

To open the container on Insanity Mode, you must turn the dial to 50 Left, then 30 Right, and finally 90 Left. Precision turning is absolutely essential here because a single mistake resets the dial completely. Cracking this version still grants you the valuable Antique Coins needed to survive the nightmarish trial.